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All the experiments followed the Guidelines of Ethical Standards for Investigation of Experimental Pain in Animals

Sodium chloride 0.9% (normal saline) contains sterile water and sodium chloride (salt) to create an isotonic solution

A preclinical safety evaluation published in ScienceDirect confirmed that BPC-157 showed no test-related toxicity in single-dose and repeated-dose studies across mice, rats, rabbits, and dogs, with no genetic or embryo-fetal toxicity detected

The NHS gives its standard hydroxocobalamin treatment as an intramuscular injection, usually delivered by a nurse or doctor

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Furthermore, LDLR gene expression can be increased by both SREBP-2-dependent and AMPK-dependent mechanisms