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Elevated NNMT expression has been observed in adipose tissue of animals with insulin resistance, and modulation of this enzyme has been shown to influence weight and metabolic function in preclinical models
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One notable finding: a study published in the Journal of Orthopaedic Research found that BPC-157 significantly improved tendon-to-bone healing in animal models of Achilles tendon detachment notably, even in the presence of corticosteroids, which normally impair healing
Persistent effects beyond two weeks suggest considering dose reduction
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