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Repeated freeze-thaw cycles cause ice crystal formation that shears peptide bonds and precipitates the copper complex

As can be seen in the figure, all the amino acids and peptides nucleated ice at temperatures well above the procedural blank, indicating that all serve as immersion mode INPs

Combining AMPs with modern nanotechnology is one of the options for developing new antimicrobial peptide delivery systems, which is of great significance to promote the clinical application of new anti-cancer drugs of AMPs

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These trials could provide valuable insights into the effectiveness of targeting oxidative stress and mitochondrial dysfunction as a therapeutic strategy in these conditions

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