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Weight regain is the most consistent finding after discontinuing tirzepatide, as appetite suppression and metabolic effects fade

A large number of men, with no prior medical history, were found to have significant hypertension (high blood pressure)

The stakes are real

"The fact that Wegovy is the only weight loss medicine proven to reduce the risk of heart attack, stroke, or cardiovascular death in patients with known heart disease and obesity makes this access moment particularly important for eligible Medicare beneficiaries

The GLP-1 space really took off with semaglutide: first as Ozempic for type 2 diabetes in 2017, then as Wegovy for obesity in 2021

[DOI] [PMC free article] [PubMed] [Google Scholar] 90.Filippatos TD, Panagiotopoulou TV, Elisaf MS