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Although GLP-1s are generally safe for the liver, its important to check, especially before compounded meds Kidney function: to watch for stress on the kidneys, which can be exacerbated by GLP-1-induced dehydration and nausea, especially in older adults or those with preexisting conditions [1] Thyroid markers : to screen for an under-functioning thyroid gland, which can mimic or worsen weight gain