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Most users report bloating onset within the first 1 to 2 weeks of starting semaglutide or within the first week after each dose escalation

Post-marketing surveillance and clinical data suggest the risk remains low, though individuals with a personal or family history of pancreatitis face elevated concern

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Genetically, ASD can be linked to identifiable genetic syndromes, such as Fragile X, Tuberous Sclerosis, Neurofibromatosis I, ADNP syndrome, and copy number variations (Lubbers et al., 2024

The implications cascade through multiple metabolic pathways

Gastrointestinal side effectsincluding diarrhoea, constipation, and altered bowel frequencyare amongst the most commonly reported reactions