The novel GLP-1RA geniposide was found to up-regulate the expression of -cell lymphoma 2 (Bcl-2), whereas reduce the activity of caspase 3, thereby protecting dopaminergic neurons in a MPTP mouse model of PD (66)
Side effects and safety considerations The most common side effects of GLP-1 medications are gastrointestinal and include nausea, vomiting, diarrhoea, constipation, and abdominal discomfort
95% CI, 0.32 to 0.60) suicidal ideation compared to non-GLP-1 RAs anti-obesity treatments [80]
Researchers have also noted that 70% of diabetes patients discontinue GLP-1 receptor agonist treatment within two years, limiting the long-term efficacy of these drugs
& Trautmann, M
12-in-1 Weight Management Formula: MuseBeam 12-in-1 GLP-1 Support Weight Loss Probiotic Capsules deliver a robust 1500 mg blend including Berberine, Cinnamon, Turmeric, Resveratrol, Garcinia, Raspberry Ketone, and more to support healthy fat metabolism and appetite regulation