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Reconstitution math Concentration = total mg in vial / volume of water added For a 10 mg vial: Add 1 mL of bacteriostatic water = 10 mg/mL concentration Add 2 mL of bacteriostatic water = 5 mg/mL concentration Add 0.5 mL of bacteriostatic water = 20 mg/mL concentration For a 30 mg vial: Add 1 mL = 30 mg/mL concentration Add 1.5 mL = 20 mg/mL concentration Add 3 mL = 10 mg/mL concentration Your prescriber or pharmacist should specify the exact volume to add

In addition to HbA1c measurement, SURPASS3 included a continuous glucose monitoring substudy to evaluate 24hour glucose profiles, as well as a magnetic resonance imaging (MRI) substudy to examine the effect of treatment on liver fat content and other measures, such as visceral fat

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4 Because hepatic steatosis is mechanistically tied to hepatic insulin resistance, this pronounced de-fatting of the liver is a plausible contributor to improved whole-body insulin sensitivity that is at least partly distinct from generic weight loss

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Dielschneider, R