Caulada-Benedetti, Z., Al-Zamel, F., Sher, A
Mesoporous silica nanoparticles have been utilized for selective internalization in tumor cells with endosomal escape, where the particles were decorated by self-immolative GSH-cleavable linkers as smart gatekeepers to prevent premature release 81
It is to restore immune tolerance, the state where the immune system correctly identifies self-tissue as friendly and stops attacking it
Ribas A, and Wolchok JD (2018) Cancer immunotherapy using checkpoint blockade Science 359 (6382) 13501355 PMID: 29567705 PMCID: 7391259 2
Drug solutions, typically 5 mg/ml in HPLC-grade water (except for Dihexa, prepared in DMSO), were added to rat serum, and the mixture was incubated at 37C
How is the blend reconstituted