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Neuroprotective Effects Preliminary Research Emerging research suggests DSIP may have significant neuroprotective properties, reducing oxidative stress and neuronal damage in experimental models of brain injury and neurodegenerative conditions

756 Overexpression of ACSL4 exacerbates cerebral I/R injury in rodents, while genetic or pharmacological reduction of ACSL4 effectively prevents cerebral I/R injury

Experiments indicate that paeonol markedly impedes IL-1-induced ferroptosis and inflammation in chondrocytes, partly through the AMPK/Nrf2/GPX4 axis ( in vitro and in vivo to alleviate DMM-induced OA

PMID: 36129147

A peer-reviewed study found that GHRP-2 reduced expression of Cd86, Nos2, and tnfa (all with statistical significance at P less than 0.01), suggesting inhibited M1 macrophage polarization

2008;294(3):L478-L488