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Laboratory studies inclusive of plasma acetaminophen and plasma salicylate levels (if there is any concern of a coingestant) should be obtained, in addition to a complete blood count, electrolytes, coagulation studies (prothrombin time and partial thromboplastin time), liver transaminase (alanine transaminase and aspartate transaminase) levels, and bilirubin level
Future trials should also measure important outcomes such as the clinical signs and symptoms of vitamin B 12 deficiency, health related-quality of life, socioeconomic effects, and report adverse events adequately, preferably in a primary care setting. Clinical practice guidelines British Columbia Medical Services Commission (MSC)
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These variations may be greater when markets are volatile or subject to unusual conditions
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