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- Light diuretic, meaning no excess fluid retention

Novo is not alone in investing in combination approaches: in AstraZenecas 2023 announcement of its acquisition of Eccogenes GLP-1 program, the manufacturer noted that they intend to combine the GLP-1 asset with other products in their portfolio (e.g., Farxiga, baxdrostat) in an effort to address obesity comorbidities (e.g., heart disease, kidney disease, metabolic syndrome)

Age-related changes in gut function may also influence GLP-1 production, though there is no definitive consensus on this relationship

Biomed Pharmacother 2021;140:111778.ArticlePubMed 58

Their effects on bowel transit lower in the gut appear more variable and may differ between individuals and medications

Store all peptide-containing products refrigerated separately from acid or retinoid formulations