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Safety Profile and Side Effects Safety is the top priority for any treatment affecting the brain

Macrophages are especially important in this process and appear to be primary producers of MGF in the setting of muscle cell inflammation

NAD+ Boosters (e.g., NMN or NR) : While not peptides, NAD+ precursors can be stacked with FOXO4-DRI to support mitochondrial function and cellular energy, complementing its senolytic action

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Recovery and sleep quality: anecdotal reports are common, but no validated outcome measures in published trials

A fully virtual program with no in-person touchpoint should raise questions, especially for the first cycle