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In September 2023 the FDA placed BPC-157 in Category 2 of its 503A interim bulk-substances policy, citing immunogenicity and peptide-characterization concerns, effectively excluding it from the 503A compounding bulk-substances list

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Intranasal preparations of glutathione appear to be safe and well tolerated and have been used by some compounding pharmacies to treat a variety of nervous system diseases for over 15 years

In 7 of 18 patients (38.9%), hyperpigmentation from doxycycline occured within 1 month

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