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Are they safe for elderly patients

Mechanistic studies reveal that GLP-1 RAs activate neurons in the arcuate nucleus, which are linked to hunger suppression

For type 2 diabetes , GLP-1 receptor agonists are generally considered a long-term treatment, as diabetes is a chronic progressive condition requiring ongoing management

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The results showed that the patch can achieve multi-milligram delivery, surpassing commercial semaglutide injections

It showed potential benefits in patients assessed at Child-Pugh A/B stages, including reducing liver volume and weight, and possibly improving liver stiffness and fibrosis (95% CI spans a wide range)