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Discovery of a potent SCAP degrader that ameliorates HFD-induced obesity, hyperlipidemia and insulin resistance via an autophagy-independent lysosomal pathway

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Specifically, null variants of the GSTM1 and GSTT1 alleles contain large deletions, and individuals who inherit two copies of the GSTM1 -null or GSTT1 -null alleles cannot produce the corresponding GST enzymes (54)

Altered central and blood glutathione in Alzheimers disease and mild cognitive impairment: a meta-analysis