GLP-1RAs, such as lixisenatide, not only rely on -cell function and glucagon suppression, but also assist to lower glucose by other (insulin-independent) mechanisms such as delayed gastric emptying, underlying the clinical utility of GLP-1RAs as adjuvant therapy to basal insulin in longstanding T2DM [14]
These all drugs falls under competitive inhibitors and founded to be responsible for about 70% of inhibition of plasma DPP-4 with some reported side effects such as nasopharyngitis, respiratory tract infections, headache and major setback is founded to be pancreatitis and hypersensitive reactions [68]
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This dual action could lead to better management of both diabetes and osteoporosis
Also known as thrombocytes, the platelets are blood components that aid in the process of blood clotting