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In comparison, in an Ecuadorian kindred with GH receptor deficiency and very low levels of IGF-I, rates of cancer and diabetes were markedly reduced compared to unaffected people in the same communities (39)

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Funding This study was supported by the Special Fund Project of Yancheng Science and Technology Bureau (No.YCBE202475), the Medical Research Project of Yancheng Health Commission (No.YK2023130), and the Special Scientific Research Fund for Clinical Medicine of Nantong University (No.2024LZ006), (2024LZ008)

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