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After final alkylation, all samples were diluted (1:1) with 20% ACN/0.1% FA containing 50 nM of deuterated internal standards and analyzed by LC-MS

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Known for their potential to enhance fat metabolism, improve physical performance, and support overall health, L-carnitine has become a staple in the world of dietary supplements

Additionally, the impact of anti-diabetic drugs (beyond SGLT2 inhibitors) on renal ferroptosis is understudiedwhether insulin or GLP-1 agonists directly modulate ferroptosis pathways or indirectly via glycemic control requires clarification