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BPC-157 complements this by mitigating drug-induced nephrotoxicity and ischemia-reperfusion damage, preserving kidney function through anti-apoptotic and anti-oxidative mechanisms

They also found that the kidney cell powerhouses, called mitochondria, are particularly impacted by acute and chronic inflammation and that the protein they delivered restored mitochondrial function

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We hypothesised that the reported brainstem transcriptomic changes might reflect modulation of NTS Ppg neuron activity downstream of GIPR antagonism in the hypothalamus and therefore tested the effect of GIPR-antag on mice with ablated NTS Ppg neurons (Ppg NTS-Abl ) generated by bilateral stereotactic injection of AAV-DTA into the NTS of Ppg-Cre or control mice (Cre-negative mice receiving AAV-DTA into the NTS) (Fig

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