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This is a formidable area of research because finding stable compounds that can prevent or mitigate arrhythmias without significant side effects is a difficult, often moving-target objective in cardiology

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These occur in less than 1 percent of patients but require immediate medical attention if symptoms develop

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Mol Cell 40:893904 Tashkandi HM, Althagafy HS, Jaber FA, Alamri T, Al-Abbas NS, Shaer NA, Harakeh S, Hassanein EH (2023) Vinpocetine mitigates methotrexate-induced duodenal intoxication by modulating NF-B, JAK1/STAT-3, and RIPK1/RIPK3/MLKL signals