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Lets break down what we know about these medications when taken together
CYP2D6 poor metabolizers Citalopram steady state levels were not significantly different in poor metabolizers and extensive metabolizers of CYP2D6
[1] [3] These combined effects lead to decreased caloric intake and significant weight loss in clinical trials
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Research published in Obesity (Martins et al., 2020) demonstrated that this metabolic adaptation can reduce daily energy expenditure by 100 to 300 calories beyond what weight loss alone would predict
Diet has a massive impact
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