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The sample size was calculated to provide at least 90% power for showing bioequivalence between the 1G and 2G formulations for all three dose groups, based on the standard acceptance limits (0.80001.2500) to ensure sufficient power to confirm bioequivalence in accordance with the EMA, FDA and PMDA guidelines

Sohn, J.-W., Elmquist, J

Low amounts of dietary fibre increase in vitro production of short-chain fatty acids without changing human colonic microbiota structure

The review paper I got this data from suggests that the most likely explanation for this is that there is some other system that we arent accounting for

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