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Overlay of confocal microscopy and immunogold EM images confirmed that intracellular Gb3 puncta in tubule-like cells corresponded to silver-enhanced immunogold particle labeling for Gb3 in GLA-mutant human iPSC kidney organoids (Fig

However, for definitive conclusions, more studies with larger sample sizes are needed

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However, the possibility of underdosing, contamination, or formulation errors exists in compounded products