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Chronic hepatitis B is a challenging condition to manage due to its prolonged course, high risk of relapse, and unsatisfactory clinical outcomes, which collectively pose significant threats to patients health and quality of life [46]

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The study also showed that KD affected inflammatory markers

Besides, the GLP-1R/GGCR dual agonist, Cotadutide, was shown to relieve steatosis, inflammation and fibrosis in both Ob/Ob NASH mice model and C57BI/6J NASH mice model (131)

Importantly, GLP-1 receptor activation has also been shown to reduce amyloid- accumulation in experimental models, linking metabolic signaling directly to canonical Alzheimers pathology [14]