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These systemic effects are uncommon and typically mild

Deadpan Snarker: Not seen much in the series proper, but the prologue episode Passage of the Stars reveals him to have a mild streak of this, at least with Lexshue

Monetti M, Levin MC, Watt MJ, Sajan MP, Marmor S, Hubbard BK, Stevens RD, Bain JR, Newgard CB, Farese RV Sr, Hevener AL, Farese RV Jr (2007) Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver

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