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IHC showed a significantly higher expression of RhoA in OA than in undamaged subchondral bone (Fig

Once in the bloodstream, they can trigger systemic inflammation and autoimmune responses

& Davis, M.C

Dyskinisias tend to occur in people who are taking levodopa who also have more neurodegeneration in the brain, that is, when the disease has progressed

Clinical studies have shown that patients taking tirzepatide not only experienced better glycemic control but also lost a notable amount of weight compared to those on traditional diabetes medications

These metabolic-derived DAMPs, together with potential pathogen-associated molecular patterns (PAMPs) in PCC, may synergistically enhance immune cell activation, forming a critical link between mitochondrial metabolic dysfunction and the subsequent inflammatory response