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Reference: Antisense oligonucleotide DGAT-2 inhibitor, ION224, for metabolic dysfunction-associated steatohepatitis (ION224-CS2): results of a 51-week, multicentre, randomised, double-blind, placebo-controlled, phase 2 trial by Rohit Loomba, Erin Morgan, Keyvan Yousefi, Dan Li, Richard Geary, Sanjay Bhanot and Naim Alkhouri, 23 August 2025, The Lancet
The STEP-1 program showed people regained a large portion of lost weight within a year after stopping semaglutide, and randomized withdrawal studies for tirzepatide have the same pattern
Tirzepatide carries a boxed warning regarding thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma or MEN 2
I am down another twenty-two pounds in four months and feel like myself again