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A joint inspection by the South African Health Products Regulatory Authority and the South African Pharmacy Council found iDexis was producing GLP-1 medicines, including tirzepatide, for broader commercial distribution beyond what regulations allow

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At the highest dose studied, retatrutide also produced weight loss approaching the range often seen after bariatric surgery, although surgery and medication should not be viewed as equivalent treatments

HbA1c down 1.91 pp Most trials report mean differences