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Case reports describe serious systemic toxicity and rhabdomyolysis at mega-doses (around 6 mg) [4]

A 200-pound person might lose 10-30 pounds, but outcomes depend on baseline health, genetics, adherence, and lifestyle

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Elevated cortisol is linked to increased appetite, fat storage around the midsection, and insulin resistancethree barriers to sustainable weight loss

This, in part, helps you reduce food intake and ultimately, enables you to lose weight in combination with other healthy lifestyle changes, including exercise and a reduced-calorie diet (3)

Systolic blood pressure was also decreased