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Higher body mass increases mechanical load across joints, accelerating cartilage wear with every step. Obesity contributes to systemic inflammation and metabolic dysfunction that can directly affect joint tissues, even in non-weight-bearing joints, he added

Frequently Asked Questions How do I know if my lack of weight loss is genetic versus lifestyle-related

They choose different foods

Only Zepbound is approved by the US Food and Drug Administration (FDA) for weight loss and management

Wegovy is the brand approved for chronic weight management, while Ozempic is approved for type 2 diabetes

Lost more weight at each check-in point during the study (3 months, 6 months, and 1 year) A separate study of adults with type 2 diabetes had similar findings