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Lindquist S, Stangel M
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compounds that target antioxidant defense system molecules: superoxide dismutase' catalase, glutathione, glutathione peroxidase, glutathione reductase, glutathione-S-transferase, heme oxygenase, Nrf-2, kidney injury molecule-1, vitamin E, N-acetylcysteine, amifostine, ebselen ans allopurinol
Additional, supplementation of sodium pyruvate and JX06 in GGCT-knockdown cells confirmed that this regulatory effect of GGCT-mediated changes in ROS was independent of energy metabolism pathways
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It is also possible that insulin resistance is the link between low GH levels and MASLD, as insulin directly suppresses pituitary GH secretion (129)
