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Large-scale, prospective trials are needed to confirm its long-term safety and efficacy
Inhaled corticosteroids (for asthma), systemic prednisone, and immunosuppressants used in autoimmune disease or post-transplant care all significantly reduce local and systemic immune competence, allowing Candida to proliferate without adequate immune restraint
This section delineates the dysregulation of MQC pathways in age-related neurological deterioration and neurodegenerative disorders, providing a mechanistic framework to decipher the pathogenic cascades driving mitochondrial dysfunction
Zheng X, Lin D, Zhang Y, et al
Glutathione might inhibit the effects of cerebral infarction and enhance antiapoptotic signaling after ischemic stroke, suggesting that GSH may be a potent therapeutic antioxidant that can attenuate severe pathologies after ischemic stroke, and stimulating GSH synthesis through administration of GSH precursors and micronutrients like selenium can optimize GSH and GSH peroxidase for optimal antioxidant defense in cerebral ischemia (155, 156)