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Sadjadi R, Sullivan S, Grant N, Thomas SE, Doyle M, Hammond C, Duong R, Corre C, David W, Eichler F (2020) Clinical myopathy in patients with nephropathic cystinosis

The peptide is small enough (three amino acids plus a copper ion) to penetrate the stratum corneum, particularly when formulated with phospholipid-based delivery systems that enhance dermal absorption

597,598 In addition to its role in macrophages, itaconate plays a pivotal role in Th17/Treg cell differentiation through metabolic and epigenetic reprogramming

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That may include different treatments for a targeted approach

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