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Ventral hippocampus WD-fed rats receiving GE2 treatment had higher levels of IL-1 than SD fed rats receiving GE2, regardless of sex (treatment and diet interaction: p = 0.030, Cohens d =0.589

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During tumor progression, macrophage-derived TGF-1 can inhibit transcription through SMAD signaling, thereby promoting ferroptosis (85) and thus representing a complex interplay between immunosuppressive cytokines and ferroptotic mechanisms

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