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doi: 10.3389/fimmu.2020.00374 141 RamagliaVSheikh-MohamedSLeggKParkCRojasOLZandeeSet al

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Research indicates that upon MC1R binding, MT-1 triggers the cAMP signaling cascade, leading to activation of protein kinase A (PKA) and subsequent upregulation of microphthalmia-associated transcription factor (MITF)