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Within AT, a subpopulation of M2 (anti-inflammatory) macrophages exist that are iron-rich and can take up excess iron and release it in response to local deficiency [47]

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Community protocols on TRT describe: 1-2 mg subcutaneous daily (FDA-approved dose: 2 mg) 6-12 month protocols for visceral fat reduction Monitoring waist circumference, fasting glucose, and IGF-1 For men tracking their body composition changes on TRT, adding tesamorelin can accelerate the visceral fat reduction that typically takes 6-12 months on testosterone alone