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Cisneros, B

Organoid-based expansion of patient-derived primary alveolar type 2 cells for establishment of alveolus epithelial Lung-Chip cultures

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These free radicals trigger enzymatic reactions, leading to oxidative damage to the cell membranes as well as the production of toxic metabolites and cell injury involving DNA, proteins, and lipids (63, 64)

Overall, metal dyshomeostasis is closely linked to various events in AD such as amyloidosis, tauopathy, oxidative stress, and neuronal death

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