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We upregulated the expression of GCLC, GSS, or SLC7A11 in VRK2-KD PC cells, and investigated the effects of these genes on cell viability, ROS and GSH levels when provided exogenous ROS ter-tbutyl hydroperoxide (TBHP)

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Conversely, we found that disruptions in several genes related to ROS mitigation and polyamine and reductant metabolism often increased antibiotic susceptibility (Supplementary Fig

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Its high prevalence poses significant social burdens, severely affecting physical and mental health, with rising trends in drug abuse 1,2,3,4

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