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JCI Insight 5:32213703

Every surgical plan is individualized

How PlexusDx Supports a More Personalized Approach PlexusDx's Precision Peptide Genetic Test may help provide context about your predisposition in key GLP-1 and GIP receptor pathwaysspecifically variants in GLP1R (rs6923761) and GIPR (rs1800437)that can inform discussions with your provider about expected response patterns and whether personalized dosing or formulation choices might optimize your outcome

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26 27 Additionally, GLP-1-mediated modulation of pain pathways, particularly via microglial activation in the caudal trigeminal nucleus, may exacerbate central sensitization and worsen headache symptoms

doi: 10.1111/jdv.17079