Evid-Based Pract
During development and progression of atherosclerosis, Nrf2 signaling modulates many physiological and pathophysiological processes, like regulation of lipid homeostasis, CD36 gene expression regulation, foam cell formation, macrophage polarization, immunity regulation (Th2 differentiation and inhibition of pro-inflammatory gene expression through NFB down-regulation), redox regulation and inflammation, improvement of endothelial dysfunction, as well as GSH synthesis and utilization (234245)
However, the difference between the short-term and long-term treatments may rather be caused by the aging of the tested mice than by the long-term treatment
doi: 10.1080/17425247.2023.2237408
What is Glutathione, and How Does it Help Mitigate the Effects of Stress and Pollution on the Skin
That is why antioxidants are very important to our body