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However, a more comprehensive view of the full spectrum of alterations in zinc homeostasis can improve the understanding of the mechanisms underlying obesity and its associated comorbidities and develop novel therapeutic strategies aimed at reducing the impact of obesity

The peer-reviewed record for tirzepatide includes multiple Phase 3 trials, real-world observational cohorts, and mechanistic pharmacology studies

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Clinical trials consistently show that tirzepatide produces greater weight loss than semaglutide, with average reductions of 15 to 22% of body weight compared to 10 to 15% for semaglutide

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