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Visceral fat reduction is especially valuable because this fat depot is strongly associated with metabolic dysfunction and health risks

If low levels of B 12 remain for a long time, the condition also can lead to irreversible damage to nerve cells, which can cause the following symptoms: numbness and tingling in the hands and feet difficulty walking muscle weakness irritability memory loss dementia depression psychosis

At 75mg daily, most protocols observe metabolic effects within 24 weeks

In those cases, correcting B12 can improve energy and wellbeing

After 16 weeks of treatment the observed mean change from baseline in body weight was -4.8%, -8.6% and -8.3%, respectively for petrelintide versus -1.7% for placebo

Compounded versions of both range from $100-$500 per month