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Additionally, a study showed the antiseizure effect of ALC (100 mg/kg) in the kainate murine model of temporal lobe epilepsy by attenuating status epilepticus and reducing oxidative stress and neuroinflammation (Tashakori-Miyanroudi et al., 2022)

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When oxidative stress is high, glutathione levels can drop, making it harder to get deep, restorative sleep

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Compound 36 also exhibited good efficacy in oral glucose tolerance tests, demonstrating great DPP-4 inhibitory activity (IC 50 = 0.017 M) and moderate selectivity against DPP-4 in both ICR and KKAy mice

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