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Modelling changes in glutathione homeostasis as a function of quinone redox metabolism

Helps reverse the synthesis of melanin, turning eumelanin (dark pigment) to pheomelanin (light pigment), thereby reducing pigmentation and dark spots

Partial correlations were further tested to control for age, smoking status, gender and ethnicity

A meta-analysis of 26 RCTs (n=3,864) found that NAC (typically 600 mg twice daily) reduced the incidence of contrast-induced nephropathy by 40% (OR 0.60, 95% CI 0.44-0.81) (Gonzales et al., BMC Med, 2007) [67]

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