Hyperandrogenism is associated with earlier age of onset of idiopathic intracranial hypertension in women
Four drivers account for most switches
Within only a few years, reports of cardiac valvulopathy associated with fenfluramine and dexfenfluramine (particularly in combination with phentermine) resulted in withdrawal of these two agents from the market
The oral semaglutide arm demonstrated improvements of 0.02, 0.23 and 0.11 QALYs compared to the liraglutide, lixisenatide and dulaglutide arms, respectively
Bachem Holding, listed on the Swiss exchange, has transformed its business mix significantly in response to GLP-1 demand, with semaglutide and related GLP-1 peptides now representing its single largest revenue segment
Some patients with optimized GLP-1 receptor function may maintain appetite suppression effects slightly longer, even as drug levels decline