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trend does not mirror global GLP-1 uptake

A systematic review and meta-analysis finds that GLP-1-based treatments drive clinically meaningful weight loss mainly through fat reduction, but experts warn that preserving muscle remains essential for long-term metabolic health

Dina Peralta-Reich, MD, FAAP, FOMA, and Director of New York Weight Wellness Medicine said that the gastrointestinal side effects of these medications, like nausea and vomiting, may be worse in older people, which may set them up for dehydration, weakness, or nutritional deficiencies. Monitoring water intake can be challenging, and it is crucial to avoid dehydration, which may result in dizziness, falls, fainting, and possibly fractures, she said

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