2015;6:02481 Hoyles L, Pontifex MG, Rodriguez-Ramiro I, Anis-Alavi MA, Jelane KS, Snelling T, et al
Exenatide once weekly plus dapagliflozin once daily versus exenatide or dapagliflozin alone in patients with type 2 diabetes inadequately controlled with metformin monotherapy (DURATION-8): a 28 week, multicentre, double-blind, phase 3, randomised controlled trial
doi: 10.3389/fendo.2021.694284 26
BioDrugs 29 , 215239 (2015)
Key Benefits Helps lower A1C in adults with type 2 diabetes Reduces appetite and promotes weight loss Decreases risk of major adverse cardiovascular events in patients with T2DM and heart disease Convenient once-daily injection No risk of hypoglycemia when used alone (without insulin or sulfonylureas) Side Effects Common side effects include: Nausea Diarrhea Decreased appetite Vomiting Constipation Indigestion Serious side effects (less common): Pancreatitis Gallbladder disease Kidney injury from dehydration Hypoglycemia (if used with insulin or sulfonylureas) Thyroid C-cell tumors (in animal studies) Warnings and Precautions Not for use in patients with type 1 diabetes or diabetic ketoacidosis Do not use in patients with a personal or family history of medullary thyroid carcinoma (MTC) Caution in patients with pancreatitis or gallbladder issues Monitor renal function in patients at risk for dehydration Use with caution in elderly or frail patients Alternative Medications (by Indication) Ozempic (semaglutide) Trulicity (dulaglutide) Byetta / Bydureon (exenatide) Rybelsus (oral semaglutide) Mounjaro (tirzepatide) Saxenda (liraglutide, approved for weight loss) Medication FAQs (Patient-Oriented Answers) What is Victoza used for
Deficiencies in this important Vitamin can show symptoms in the form of hair thinning or shredding more than usual
