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The difference is in degree of effectiveness and mechanism
(Notably, tirzepatide in diabetics also lowers HbA1c, and even though the OSA trial excluded diabetics, the drugs metabolic effects would likely benefit prediabetic OSA patients by improving glycemic control.) This multifaceted impact can be viewed as a holistic approach to a cardiometabolic syndrome, where OSA is one piece of the puzzle
supplementary file 6)
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