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10.1016/j.chemphyslip.2014.03.002 25 DeasE.CremadesN.AngelovaP
Weeks 14: (2.5 mg starting dose) The starting dose is kept low on purpose
Consistent with Oga deletion, pharmacological inhibition of Oga, which induces acute elevation of O-GlcNAcylation, has been shown to attenuate hippocampal activity by diminishing the intrinsic excitability of CA1 neurons and excitatory synaptic transmission at Schaffer collateral-CA1 synapses [80]
It defined individual distinct RCD modalities, including intrinsic and extrinsic apoptosis, autophagy-dependent cell death, entotic cell death, ferroptosis, lysosome-dependent cell death, mitochondrial permeability transition-driven necrosis, mitotic death, necroptosis, NETotic cell death, parthanatos, and pyroptosis [4]
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